Not to be confused with the unincorporated area of Wylie, Taylor County, Texas, in the city limits of Abilene.Wylie is a city once solely located in Collin County but now extends into neighboring Dallas and Rockwall counties in the U.S. state of Texas. It is located on State Route 78 about 20 miles northeast of central Dallas and centrally located to nearby Lavon Lake and Lake Ray Hubbard.